Treating Hypertension and the role of ARBs: Update on ARBs, Clinical Pharmacology and Clinical Implications. Chair: Simon Roger (Australia)
In both developed and emerging economies hypertension is a major cardiovascular risk. There are numerous options available to treat hypertension with ARBs playing a major role. However, unmet needs are still prevalent in anti-hypertensive treatment, such as adequate and sustained blood pressure control and better tolerability. Furthermore, ethnicity and genetic factors, in particular the renin-angiotensin system gene polymorphisms, maybe important in both the development and treatment of hypertension. Thus, treatment of hypertension remains challenging and new treatments are essential to effectively control blood pressure.
During this symposium, several aspects of hypertension treatment will be discussed, including:
• Currently available ARBs and differentiation of these ARBs by pharmacology and molecular mechanisms
• Treatment paradigms in Asian and Western countries
• Factors influencing treatment such as ethnicity and genetics.
• New ARBs and the role of diuretics in the treatment of hypertension- what makes them different?